Bouhifd, M. et al. Quality assurance of metabolomics. ALTEX 32, 319-326 (2015).

Buick, J.K. et al. Integration of metabolic activation with a predictive toxicogenomics signature to classify genotoxic versus nongenotoxic chemicals in human TK6 cells. Environ Mol Mutagen 56, 520-534 (2015).

Fasani, R.A. et al. The Human Toxome Collaboratorium: A Shared Environment for Multi-Omic Computational Collaboration within a Consortium. Front Pharmacol 6, 322 (2015).

Li, H.H. et al. Development of a toxicogenomics signature for genotoxicity using a dose-optimization and informatics strategy in human cells. Environ Mol Mutagen 56, 505-519 (2015).

Moffat, I. et al. Comparison of toxicogenomics and traditional approaches to inform mode of action and points of departure in human health risk assessment of benzo[a]pyrene in drinking water. Crit Rev Toxicol 45, 1-43 (2015).

Vantangoli, M.M., Madnick, S.J., Huse, S.M., Weston, P. & Boekelheide, K. MCF-7 Human Breast Cancer Cells Form Differentiated Microtissues in Scaffold-Free Hydrogels. PLoS One 10, e0135426 (2015).

Maertens, A. et al. Metabolomic network analysis of estrogen-stimulated MCF-7 cells: a comparison of overrepresentation analysis, quantitative enrichment analysis and pathway analysis versus metabolite network analysis. Arch Toxicol (2016).

Kleensang A, Vantangoli MM, Odwin-DaCosta S, Andersen ME, Boekelheide K, Bouhifd M, Fornace AJ, Li H, Livi CB, Madnick S, Maertens A, Zhao L, Rosenberg M, Yager JD, Hartung T: Genetic variability in a frozen batch of MCF-7 cells invisible in routine authentication affecting cell function. Nature Scientific Reports 2016 (in press)

Bouhifd, M., Andersen, M.E., Baghdikian, C., Boekelheide, K., Crofton, K.M., Fornace, A.J., Jr., Kleensang, A., Li, H., Livi, C., Maertens, A., McMullen, P.D., Rosenberg, M., Thomas, R., Vantangoli, M., Yager, J.D., Zhao, L., Hartung, T., 2015. The human toxome project. ALTEX 32, 112-124.

Bouhifd M, Hogberg HT, Kleensang A, Maertens A, Zhao L, Hartung T. 2014. Mapping the human toxome by systems toxicology. Basic & Clinical Pharmacology & Toxicology 115:24-31. doi: 10.1111/bcpt.12198

Kleensang A, Maertens A, Rosenberg M, FitzpatrickS, Lamb J, Auerbach S, et al. t4 workshop report: Pathways of Toxicity. ALTEX. 2013. t4 Workshop Report: Pathways of Toxicity. Altex 31:53-61. doi: 10.14573/altex.1309261

Hartung T, van Vliet E, Jaworska J, Bonilla L, Skinner N and Thomas R. Food for thought… systems toxicology. ALTEX 2012, 29: 119-128.

Bouhifd M, Hartung T, Hogberg HT, Kleensang A and Zhao L. Review: Toxicometabolomics. J. Appl. Toxicol. 2013 May 30. doi: 10.1002/jat.2874.

Hartung T, Luechtefeld T, Maertens A and Kleensang A. Food for thought…Integrated Testing Strategies for Safety Assessments. ALTEX 2013, 30: 3-18

Hartung T. Pathways of Toxicity Mapping Center (PoToMaC). In: Spielmann H and Seidle T. Alternative Testing Strategies: Progress Report 2012 & AXLR8-3 Workshop Report on a “Roadmap to Next Generation Safety Testing Under Horizon 2020.” 165-169.

Ramirez T , Daneshian M, et. al. t4 Metabolomics in Toxicology and Preclinical Research. ALTEX 2013;30:(2): 209-225.

Manuscripts in Preparation or Review

Pendse, S.N. et al. Information-dependent Enrichment Analysis Reveals Time-dependent Transcriptional Regulation of the Estrogen Pathway of Toxicity. Arch Toxicol (2016) (in review)      

Chen, R.X. et al. Estrogenic transcriptional responses by metal toxicants (in preparation)